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The Three-Pound Enigma: The Human Brain and the Quest to Unlock Its Mysteries

de Shannon Moffett

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The average human brain weighs three pounds--80 percent of which is water--and yet it's capable of outstripping the computational and storage capacities of the most complex computer. But how the mind works remains one of humankind's greatest mysteries. With boundless curiosity and enthusiasm, Shannon Moffett, a Stanford medical student, takes us down the halls of neuroscience to the front lines of cutting-edge research and medicine to meet some of today's most extraordinary scientists and thinkers, all grappling with provocative questions: Why do we dream? How does memory work? How do we see? What happens when we think? Each chapter delves into a different aspect of the brain, following the experts as they chart new ground. Moffett takes us to a lab where fMRI scans reveal the multitude of stimuli that our brains unconsciously take in; inside an operating room where a neurosurgeon removes a bullet from a patient's skull; to the lab of Christof Koch, a neuroscientist tracking individual neurons in order to crack the code of consciousness; and to a research lab where scientists are investigating the relationship between dreams and waking life. She also takes us beyond the scientific world--to a Zen monk's zendo, where she explores the effects of meditation on the brain; inside the home of a woman suffering from dissociative identity disorder; to a conference with the philosopher Daniel Dennett, who uses illusions, magic, tricks, and logic to challenge our assumptions about the mind; and to the home of the late Nobel Laureate Francis Crick, co-discoverer with James Watson of DNA's double-helix structure. Filled with fascinating case studies and featuring a timeline that tracks the development of the brain from conception to death, The Three Pound Enigma is a remarkable exploration of what it means to be human.… (mais)
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Simplifying brain research for the amateur reader is a daunting task that Moffett achieves with straight-forward explanations and a contagious enthusiasm. ( )
  aholtry | May 3, 2009 |
What could be more fascinating than the human brain? In the tradition of Oliver Sacks, Shannon Moffett takes us on a journey to meet the people who study the brain and learn their discoveries. Written as a series of essays, interspersed with little tutorials describing the brain at different periods of development, The Three-Pound Enigma provides a lively, yet meandering, tour through the modern science of the human brain. Rather than describing the facts of the brain in detached and scholarly style, Moffett humanizes the quest for the brain’s secrets by visiting the sundry cast of characters, which include renowned philosopher of the mind, Daniel Dennett, dream researcher Bob Stickgold, and neurosurgeon Roberta Glick.
While this approach may make each individual essay more interesting, ultimately the focus on personal narrative undermines the coherence of the book. The collection thus seems like a series of episodes in a PBS series rather than a unified volume about modern cognitive science. Rather than gently guided from one topic to the next logical step, the reader is awkwardly shuffled from a dream laboratory, to the controversial (and some would say marginal) topic of dissociative identity disorder (or multiple personalities) to the infant field of neuroethics. Despite this flaw, and the weakness of certain chapters relative to others, those who enjoyed Sacks’ Anthropologist on Mars or other popular work on the brain should find this book an engaging read about the fascinating bridge between brain and mind.
  criener | Jun 4, 2007 |
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The average human brain weighs three pounds--80 percent of which is water--and yet it's capable of outstripping the computational and storage capacities of the most complex computer. But how the mind works remains one of humankind's greatest mysteries. With boundless curiosity and enthusiasm, Shannon Moffett, a Stanford medical student, takes us down the halls of neuroscience to the front lines of cutting-edge research and medicine to meet some of today's most extraordinary scientists and thinkers, all grappling with provocative questions: Why do we dream? How does memory work? How do we see? What happens when we think? Each chapter delves into a different aspect of the brain, following the experts as they chart new ground. Moffett takes us to a lab where fMRI scans reveal the multitude of stimuli that our brains unconsciously take in; inside an operating room where a neurosurgeon removes a bullet from a patient's skull; to the lab of Christof Koch, a neuroscientist tracking individual neurons in order to crack the code of consciousness; and to a research lab where scientists are investigating the relationship between dreams and waking life. She also takes us beyond the scientific world--to a Zen monk's zendo, where she explores the effects of meditation on the brain; inside the home of a woman suffering from dissociative identity disorder; to a conference with the philosopher Daniel Dennett, who uses illusions, magic, tricks, and logic to challenge our assumptions about the mind; and to the home of the late Nobel Laureate Francis Crick, co-discoverer with James Watson of DNA's double-helix structure. Filled with fascinating case studies and featuring a timeline that tracks the development of the brain from conception to death, The Three Pound Enigma is a remarkable exploration of what it means to be human.

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