Based on the 12th International Symposium on Parkinson's Disease, this comprehensive volume provides reviews of the genetics, pathophysiology, and treatment of Parkinson's disease. Topics discussed include genetic studies of familial Parkinsonism; neural mechanisms underlying levodopa-induced dyskinesia; psychosis and hallucinations in Parkinson's disease; current controversies in pallidal surgery; new delivery systems for anti-Parkinsonian drugs; and new pharmacologic agents for treatment of the disease.