Collects material from Strange Tales (1951) #110-111 and #114-146 and Amazing Spider-Man Annual #2. A vain man driven by greed and hubris, Dr. Stephen Strange was a world-renowned surgeon until the night a car accident crippled his hands. Broken and destitute, he journeyed to Tibet to seek a cure from a legendary healer. There he found not a man of medicine, but the venerable Ancient One - and the path to the mystic arts! From Doctor Strange's eerie Greenwich Village home, Stan Lee and Steve Ditko created new dimensions and otherworldly terrors unlike anything seen before. These classic first stories remain as influential today as they were to 1960s counterculture. In this premiere volume, experience the debut of iconic characters including Baron Mordo, Eternity, Dormammu and the Mindless Ones - as well as Strange's faithful servant Wong and the mystic mistress Clea!.