Clique em uma foto para ir ao Google Livros
Carregando... The Polymerase Chain Reactionde Kary B. Mullis
Nenhum(a) Carregando...
Registre-se no LibraryThing tpara descobrir se gostará deste livro. Ainda não há conversas na Discussão sobre este livro. Sem resenhas sem resenhas | adicionar uma resenha
James D. Watson When, in late March of 1953, Francis Crick and I came to write the first Nature paper describing the double helical structure of the DNA molecule, Francis had wanted to include a lengthy discussion of the genetic implications of a molecule whose struc ture we had divined from a minimum of experimental data and on theoretical argu ments based on physical principles. But I felt that this might be tempting fate, given that we had not yet seen the detailed evidence from King's College. Nevertheless, we reached a compromise and decided to include a sentence that pointed to the biological significance of the molecule's key feature-the complementary pairing of the bases. "It has not escaped our notice," Francis wrote, "that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material." By May, when we were writing the second Nature paper, I was more confident that the proposed structure was at the very least substantially correct, so that this second paper contains a discussion of molecular self-duplication using templates or molds. We pointed out that, as a consequence of base pairing, a DNA molecule has two chains that are complementary to each other. Each chain could then act ". . . as a template for the formation on itself of a new companion chain, so that eventually we shall have two pairs of chains, where we only had one before" and, moreover, " ... Não foram encontradas descrições de bibliotecas. |
Current DiscussionsNenhum(a)
Google Books — Carregando... GênerosClassificação decimal de Dewey (CDD)574.87Natural sciences and mathematics Life Sciences, Biology Biology Molecular Biology Cell biologyClassificação da Biblioteca do Congresso dos E.U.A. (LCC)AvaliaçãoMédia: Sem avaliação.É você?Torne-se um autor do LibraryThing. |