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If so, as an evolutionary biologist, I find the first and final (6th) editions to be the most essential. The first for the fact that it was that version that revolutionized sciences and it is closer to his original idea on the subject. The sixth, however, is also important as it incorporated (actually accumulated) many of the necessary revisions after receiving critiques and after having thought more on the topics (there is an added chapter in fact).
Hope that helps.
The Annotated Origin: A Facsimile of the First Edition of On the Origin of Species
I haven't seen it, but it sounds like a great idea, and I've read some positive reviews.
For this, I would recommend the Harvard University Press facsimile prefaced by Mayr, where he discusses these issues.
Over a decade ago, I picked up the cheapest version which I could get my hands on, and then gifted it (with the idea of eventually purchasing a better edition).
I'll look into all of your suggestions!
I could take or leave Watson's commentary to be honest, but I found having all of Darwin's work regarding evolution, in a single volume to be extremely helpful and informative.